| Date | Location | Result | |
| Nov 06, 2010 | Trinity University | Colorado College 3, DePauw University 1 (24-26,25-22,25-17,25-18) | Box score |
| Nov 06, 2010 | Trinity University | DePauw University 3, Centre College 2 (29-27,25-15,15-25,23-25,15-12) | Box score |
| Nov 05, 2010 | Trinity University | DePauw University 3, Rhodes College 0 (25-21,25-17,25-21) | Box score |
| 10/30/10 | Greencastle, Indiana | Marian (Ind.) 3, DePauw University 0 (25-23,25-19,25-15) | Box score |
| 10/29/10 | Greencastle, Indiana | Bluffton University 3, DePauw University 2 (22-25,25-20,25-15,16-25,15-12) | Box score |
| 10/24/10 | Atlanta, Ga. | DePauw University 3, Sewanee 0 (25-8,25-11,25-16) | Box score |
| 10/24/10 | Atlanta, Ga. | DePauw University 3, Hendrix College 2 (25-18,16-25,25-19,20-25,15-10) | Box score |
| 10/23/10 | Atlanta, Ga. | DePauw University 3, Birmingham-Southern 1 (28-30,25-16,25-22,25-21) | Box score |
| 10/23/10 | Atlanta, Ga. | DePauw University 3, Millsaps College 0 (28-26,25-20,27-25) | Box score |
| 10/16/10 | Sherman, Texas | DePauw University 3, Oglethorpe Univ. 0 (25-16,25-12,25-21) | Box score |
| 10/16/10 | Sherman, Texas | Austin College 3, DePauw University 1 (25-19,25-15,20-25,25-23) | Box score |
| 10/15/10 | Sherman, Texas | Southwestern Univ. 3, DePauw University 2 (27-29,25-13,25-16,17-25,15-12) | Box score |
| 10/15/10 | Sherman, Texas | Colorado College 3, DePauw University 0 (25-17,25-17,25-17) | Box score |
| 10/12/10 | Greencastle, Indiana | DePauw University 3, Hanover College 2 (25-22,28-26,20-25,19-25,15-13) | Box score |
| 10/3/10 | Birmingham, Ala. | DePauw University 3, Rhodes College 0 (25-16,25-19,25-18) | Box score |
| 10/3/10 | Birmingham, Ala. | DePauw University 3, Centre College 0 (25-22,25-15,25-23) | Box score |
| 10/2/10 | Birmingham, Ala. | DePauw University 3, Millsaps College 2 (25-18,25-23,23-25,21-25,15-10) | Box score |
| 10/2/10 | Birmingham, Ala. | DePauw University 3, Hendrix College 0 (25-14,25-18,25-21) | Box score |
| 9/26/10 | Sewanee, Tenn. | DePauw University 3, Sewanee 0 (25-9,25-16,25-9) | Box score |
| 9/26/10 | Sewanee, Tenn. | DePauw University 3, Austin College 1 (25-21,21-25,25-18,25-20) | Box score |
| 9/25/10 | Sewanee, Tenn. | Colorado College 3, DePauw University 2 (24-26,25-18,27-29,25-19,15-10) | Box score |
| 9/25/10 | Sewanee, Tenn. | DePauw University 3, Trinity (Texas) 2 (25-22,16-25,21-25,25-19,15-10) | Box score |
| 9/18/10 | Greencastle, Indiana | DePauw University 3, Haverford College 1 (25-22,17-25,25-18,25-22) | Box score |
| 9/18/10 | Greencastle, Indiana | Carthage College 3, DePauw University 2 (17-25,22-25,25-23,25-9,15-10) | Box score |
| 9/17/10 | Greencastle, Indiana | Susquehanna Univ. 3, DePauw University 2 (21-25,25-21,19-25,26-24,15-12) | Box score |
| 9/17/10 | Greencastle, Indiana | DePauw University 3, Marietta College 0 (25-15,25-22,25-19) | Box score |
| 9/14/10 | Greencastle, Indiana | Mount St. Joseph 3, DePauw University 1 (25-20,24-26,26-24,25-17) | Box score |
| 9/11/10 | Terre Haute, Indiana | DePauw University 3, Eureka College 0 (25-12,25-7,25-8) | Box score |
| 9/11/10 | Terre Haute, Indiana | Rose-Hulman Inst. 3, DePauw University 1 (25-23,25-20,19-25,25-16) | Box score |
| 9/10/10 | Terre Haute, Indiana | DePauw University 3, Franklin College 0 (25-8,25-14,25-9) | Box score |
| 9/10/10 | Terre Haute, Indiana | DePauw University 3, Principia College 0 (25-13,25-11,25-16) | Box score |
| 9/5/10 | St. Louis, Mo. | Washington-St. Louis 3, DePauw University 1 (25-9,25-16,24-26,25-13) | Box score |
| 9/5/10 | St. Louis, Mo. | Wis.-Platteville 3, DePauw University 0 (25-16,25-23,25-14) | Box score |
| 9/4/10 | St. Louis, Mo. | DePauw University 3, Fontbonne University 0 (25-8,25-14,25-4) | Box score |
| 9/4/10 | St. Louis, Mo. | Simpson College 3, DePauw University 0 (25-21,27-25,26-24) | Box score |
| Sep 1, 2010 | Indianapolis, Ind. | DePauw University 3, Marian (Ind.) 2 (22-25,25-21,9-25,25-21,15-12) | Box score |